The James E. Williams (DDG 95) is the U.S. Navy's 45th Arleigh Burke-class guided-missile destroyer and was named in honor of Boatswain's Mate 1st Class James E. Williams, one of the Navy's most highly decorated enlisted Sailors, having been awarded the Congressional Medal of Honor for bravery and leadership in 1966 while serving as patrol boat captain and patrol commander or River Patrol Boat (PBR) 105 on the Mekong River, Republic of Vietnam.